| Date | H/A | Opponent | Record | Div. | Result | Score | Notes |
|---|---|---|---|---|---|---|---|
| 2022-08-19 | H | Wauzeka/Seneca | 6-3 | D7 | W | 6-34 | |
| 2022-08-26 | A | Ithaca | 5-4 | D7 | W | 36-8 | |
| 2022-09-02 | H | Belleville | 8-1 | D6 | L | 30-7 | |
| 2022-09-09 | A | Mineral Point | 4-5 | D6 | W | 34-27 | |
| 2022-09-16 | A | Benton/Scales Mound/Shullsburg | 5-4 | D6 | W | 28-12 | |
| 2022-09-24 | A | Pecatonica/Argyle | 0-9 | D7 | W | 64-6 | |
| 2022-09-30 | H | Black Hawk/Warren (IL) | 6-3 | D7 | W | 18-42 | |
| 2022-10-07 | A | River Ridge | 8-1 | D7 | W | 27-13 | |
| 2022-10-14 | H | Southwestern East Dubuque | 4-5 | D7 | W | 20-44 |